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Immigrating drastically changes people’s microbiome

发布时间:2018-11-07 文章编辑:admin
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As soon as a person immigrates to the US, their 大发microbiome starts to change.

People switching from a Thai diet to an American diet exhibit a drastic reduction in microbiome diversity. Depicted here: a Thai dish (fish in chili sauce).

Immigration is a touchy subject in many parts of the world, but while some things are debatable, researchers found clear signs that the microbiome of immigrants drastically changes when they come to the US. Specifically, researchers from  the University of Minnesota and the Somali, Latino, and Hmong Partnership for Health and Wellness have studied communities migrating from Southeast Asia to the US, finding that their gut biome is immediately “Americanized.”

“We found that immigrants begin losing their native microbes almost immediately after arriving in the U.S. and then acquire alien microbes that are more common in European-American people,” says senior author Dan Knights, a computer scientist and quantitative biologist at the University of Minnesota. “But the new microbes aren’t enough to compensate for the loss of the native microbes, so we see a big overall loss of diversity.”

It has to be said that this isn’t really a good thing. Generally speaking, microbiomes from the Western world are associated with greater obesity, whereas people from developing countries tend to have more diverse and healthy microbiomes (particularly in areas where fruits and vegetables are more popular). It seems quite normal that a person’s biome would shift when the diet changes, but it’s striking to see how much diversity is lost, and how fast this happens — in only six to nine months.

“Obesity was a concern that was coming up a lot for the Hmong and Karen communities [from Thailand] here. In other studies, the microbiome had been related to obesity, so we wanted to know if there was potentially a relationship in immigrants and make any findings relevant and available to the communities. These are vulnerable populations, so we definitely try to make all of our methods as sensitive to that as possible and make sure that they have a stake in the research,” says first author Pajau Vangay.

Good microbes

The gut microbiota (also called the gut microbiome, and previously called the gut flora) is the name given to the microbe population living in our intestine. Essentially, our gut contains trillions of microorganisms, from hundreds of different species, containing 3 million genes — 150 times more than human genes.

本文源自: 环亚娱乐